… Here, we provide an overview of the many different … , more specific, and less toxic molecules
can be identified for the … least) two pathways for receptor-mediated endocytosis of suramin in …

… to this list inhibition by suramin of at least two targets within the … administration of suramin
results in multiple toxicities and the … of human colon cancer and lung cancer cells both in vitro …

… In the last two decades, appreciable progress has been … , chemotherapeutic agents have
significant toxicity and badly … In a cohort study with 15,052 colorectal cancer patients, that …

… system may act as “two compartment” targeting drugs able to exert a … Aim of this review is to
provide an overview of the role of the … Intracrine FGFs play a role in neuronal and myocardial …

… to unmodified suramin and these are also less toxic [110]. … in vitro, and it has been proposed
as a novel therapeutic agent to … PPS or isotonic saline was injected twice weekly for 6 weeks …

… resistance in MM patients, neuro-toxicities, and little efficacy in … therapeutic agent for multiple
myeloma (MM) and mantle cell … , BTZ has shown significant anticancer activity in plasma cell …

… truncated suramin derivatives were ineffective against the tumor cell … )thiazol-2-yl urea
derivatives as therapeutic agents) this year, … activity against human colon cancer cells, underwent …

… to provide a viable solution. Here, we demonstrate that the reduction of LL-37 toxicity might
be … Moreover, a comparison with other therapeutic agents having common features unveiled …

… due to their low toxicity, low drug resistance, low cost and … used as preventive and therapeutic
agents in cancer therapy. These … In this study, it has been shown that esculetin provides a …

… is suramin, a P2 receptor antagonist and antitrypanosome … to perturbagens, including
therapeutic agents, pathway and … maximize hit identification and minimize toxicity, based on our …